Every game I've tried has repeated simultaneous audio/video dropouts, though the game doesn't freeze (controller rumble still happens at expected time, and game time has passed when audio/video returns). It seems to be more common when there's more activity in the game scene, though it happens at 'quiet' times too, even in the dashboard (Rocky5) with some video modes.
It's a lot worse in PAL-60, but happens in PAL and NTSC, over component and through HDMI converter. I've tried various combinations of video modes set in Rocky5, enigmah or lpartx. Nothing working yet.
I haven't done anything hardware-wise to this thing in the ~15 years I've had it, and have only recently installed Rocky5 - seems like a hardware issue?